2 3 5 Trimethylpyrazine
pyridine pyrrole pyrazine piperidine piperazine

2,3,5-trimethylpyrazine

    Specifications

    HS Code

    151692

    Chemical Formula C7H10N2
    Molecular Weight 122.17 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Nutty, roasted, and earthy aroma
    Boiling Point 171 - 173 °C
    Melting Point -22 °C
    Density 0.996 g/cm³ at 20 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol, diethyl ether, etc.
    Flash Point 58 °C
    Vapor Pressure 0.32 hPa at 20 °C
    Refractive Index 1.500 - 1.504 at 20 °C

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    Frequently Asked Questions

    As a leading 2,3,5-trimethylpyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3,5-trimethylpyrazine?
    2% 2C3% 2C5-trimethylpentane has a wide range of main uses.
    In the field of organic synthesis, this substance is often an important raw material. Due to its unique structure, many organic compounds with special properties can be prepared through various chemical reactions. For example, halogen atoms can be introduced through halogenation reactions, and then a series of halogenated hydrocarbons can be derived. Such halogenated hydrocarbons are widely used in the synthesis of medicines and pesticides. They can be used as intermediates to construct complex molecular structures through substitution, addition and other reactions.
    In the field of fuels, 2% 2C3% 2C5-trimethylpentane also has a place. Due to its excellent combustion performance, it can improve the quality of fuel, improve combustion efficiency, and reduce pollutant emissions. In aviation fuel, appropriate addition of this substance can optimize the performance of fuel, ensure the stable operation of aircraft engines, and provide reliable power in complex environments such as high altitudes.
    In addition, in the field of research, because of its relatively clear and special structure, it is often used as a standard material. Scientists can provide reference and comparison for the study of other related compounds by accurately measuring their physical and chemical properties, and help to further explore the relationship between the structure and properties of organic compounds. In analytical chemistry, it can provide standard samples for analytical methods such as gas chromatography for calibration of instruments, determination of retention time, etc., to ensure the accuracy and reliability of analytical results.
    What are the physical properties of 2,3,5-trimethylpyrazine?
    2% 2C3% 2C5-trimethylpentane is one of the organic compounds. Its physical properties are quite characteristic.
    Looking at its state, under normal temperature and pressure, 2,3,5-trimethylpentane is in a liquid state. Due to the intermolecular forces, the structure formed by hydrocarbon atoms causes it to be liquid and flowable in the common temperature range, which is different from the easily diffused and fixed shape of the gaseous state.
    The boiling point is about 113 ° C. There is a van der Waals force between molecules. It needs to reach a certain temperature to give the molecule enough energy to overcome this force before it can change from liquid to gaseous state. This specific temperature is the boiling point. Its boiling point value is affected by factors such as molecular structure and molecular weight. The carbon chain structure and methyl distribution of 2,3,5-trimethylpentane determine the magnitude of the intermolecular forces, which in turn affect the boiling point.
    As for the melting point, it is about -113 ° C. When the temperature drops to this point, the thermal motion of the molecules weakens and an orderly arrangement forms a solid-state lattice structure. Due to the shape and interaction of the molecule, the atoms are arranged in an orderly order in its solid state, and the kinetic energy of the molecule at low temperature is not enough to destroy this ordered structure.
    The density of 2,3,5-trimethylpentane is less than that of water, about 0.74g/cm ³. Because the molecular composition is mainly hydrocarbon, the atomic weight is relatively small, and the intermolecular arrangement is relatively loose, so the unit volume mass is less than that of water, so it can float on the water surface.
    In terms of solubility, 2,3,5-trimethylpentane is insoluble in water. Water is a polar molecule, while the organic substance is a non-polar molecule. According to the principle of "similarity and miscibility", the polarity difference between the two is large and the interaction force is weak, so it is difficult to dissolve. However, in organic solvents such as ethanol and ether, the solubility is good. Because organic solvents are mostly non-polar or weakly polar, they are similar to the intermolecular forces of 2,3,5-trimethylpentane and are miscible with each other.
    What are the chemical properties of 2,3,5-trimethylpyrazine?
    2% 2C3% 2C5-trimethylpyridine is one of the organic compounds. Its chemical properties are unique and have many important properties.
    Structurally, this compound is composed of a pyridine ring connected to three methyl groups. This structure gives it specific physical and chemical properties.
    In terms of chemical properties, 2% 2C3% 2C5-trimethylpyridine is weakly basic. The nitrogen atom on the pyridine ring has lone pairs of electrons and can accept protons, so it exhibits alkalinity. However, due to the electron-giving effect of methyl groups, its alkalinity is slightly stronger than that of pyridine. This alkalinity allows it to react with acids to form corresponding salts. For example, when reacted with hydrochloric acid, 2% 2C3% 2C5-trimethylpyridine hydrochloride can be obtained.
    At the same time, the methyl group of 2% 2C3% 2C5-trimethylpyridine can participate in a variety of chemical reactions. Such as oxidation reactions, under suitable conditions, the methyl group can be oxidized to other functional groups such as carboxyl groups. Or a substitution reaction occurs, the hydrogen atom on the methyl group can be replaced by other atoms or groups. Like in halogenation reactions, the hydrogen on the methyl group can be replaced by halogen atoms to form halogenated derivatives.
    In addition, the stability of this compound also changes due to the presence of methyl groups. The methyl group enhances the electron cloud density of the molecule and plays a certain stabilizing role on the pyridine ring, making 2% 2C3% 2C5-trimethylpyridine easier to store and use under certain conditions.
    In the field of organic synthesis, 2% 2C3% 2C5-trimethylpyridine is often used as an intermediate. With its unique chemical properties, it participates in the preparation process of many organic compounds and provides an important basis for the synthesis of various complex organic molecules.
    What is the production method of 2,3,5-trimethylpyrazine?
    2% 2C3% 2C5-trimethylpyridine. Although the method of synthesis of this substance is not detailed in ancient books, it can be obtained by numerical methods based on today's chemical rationality.
    First, pyridine is used as a base and is prepared by methylation. The activity check point of the pyridine ring can be used with methylating reagents, such as iodomethane and dimethyl sulfate, under appropriate conditions. In an alkaline environment, the base can seize the hydrogen atom on the pyridine ring to generate carbon negative ions. This carbon negative ion has strong nucleophilicity and can attack the methyl carbon of the methylating reagent to form a carbon-carbon bond, and then introduce methyl. The conditions that control the reaction, such as temperature, ratio of reagents, and reaction time, can enable the introduction of 2% 2C3% 2C5-trimethyl groups into the pyridine ring at specific positions. However, this process needs to be carefully regulated to avoid side reactions.
    Second, the pyridine ring is constructed from suitable nitrogen-containing and carbon-containing small molecules through multi-step reactions, and methyl groups are introduced at the same time. For example, using β-ketone esters, aldose, ammonia, etc. as raw materials, through condensation, cyclization, etc., the prototype of the pyridine ring is first formed. During or after the reaction, the required methyl groups are introduced by suitable methylation means. This path needs to be carefully designed for the reaction steps and conditions to ensure that the reaction of each step is smooth, and the purity and yield of the product are considerable.
    Third, the method of biosynthesis may also be feasible. Find a specific microorganism, which has a specific enzyme system, and can catalyze related substrates to generate 2% 2C3% 2C5 -trimethylpyridine through biological metabolic pathways. However, this method requires the optimization of microbial screening and culture conditions, and the separation and purification of the product is also challenging. The reaction in the organism is complex and there are many impurities. It is not easy to obtain high-purity products.
    These methods have advantages and disadvantages. When actually preparing, when considering the availability of raw materials, cost, purity and yield of the product, and many other factors, the choice is made.
    In which fields is 2,3,5-trimethylpyrazine used?
    2% 2C3% 2C5-trimethylpyridine is useful in many fields. In the field of medicine, it is an indispensable raw material for the preparation of many drugs. For example, some antibacterial drugs, with the help of the unique chemical structure of 2% 2C3% 2C5-trimethylpyridine, can effectively enhance the antibacterial activity of drugs and improve the therapeutic effect. In the field of pesticides, it also plays an important role. It can be used to synthesize specific pesticide ingredients, which have high efficacy in killing or repelling pests, and has relatively little impact on the environment, contributing to the sustainable development of agriculture.
    Furthermore, in the field of materials science, 2% 2C3% 2C5-trimethylpyridine can be used as a reaction intermediate to participate in the synthesis of high-performance materials. For example, when preparing some polymer materials with special electrical and optical properties, it can adjust the molecular structure of the material, thereby optimizing the material properties.
    In the fragrance industry, 2% 2C3% 2C5-trimethylpyridine can be used to create novel and unique fragrances due to its unique odor, and can be used in perfumes, air fresheners and other products to give the product a unique flavor.
    In the field of organic synthetic chemistry, as a key organic reagent, it often participates in the synthesis of various complex organic compounds, providing organic synthetic chemists with rich synthesis paths and possibilities, helping to synthesize more organic compounds with special functions and structures.