1h Imidazo 4 5 D Pyrazine
pyridine pyrrole pyrazine piperidine piperazine

1H-Imidazo[4,5-d]pyrazine

    Specifications

    HS Code

    592015

    Chemical Formula C6H4N4
    Appearance Solid (usually)
    Odor Typically odorless
    Melting Point Data varies, needs specific study
    Boiling Point Data varies, needs specific study
    Solubility In Water Low solubility
    Solubility In Organic Solvents Moderate solubility in some organic solvents
    Density Data varies, needs specific study
    Stability Stable under normal conditions
    Pka Data varies, needs specific study
    Flash Point Data varies, needs specific study

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Imidazo[4,5-d]pyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 1H-Imidazo [4,5-d] pyrazine?
    The chemical structure of 1H-imidazolo [4,5-d] pyrazine is also. This is one of the organic compounds, formed by fusing the imidazole ring with the pyrazine ring. Looking at its structure, the imidazole ring has a dinitrogen atom and is in the shape of a five-membered ring, and the pyrazine ring contains a dinitrogen atom and is in the shape of a six-membered ring. The two are fused together and connected at a specific position to form a unique structure of 1H-imidazolo [4,5-d] pyrazine.
    In this structure, the presence of nitrogen atoms gives it many properties. Nitrogen atoms have lone pairs of electrons and can participate in many chemical reactions, such as forming hydrogen bonds and coordinating with metal ions. The dense ring structure also affects the electron cloud distribution and spatial configuration of the molecule, which in turn affects its physical and chemical properties.
    In the field of organic synthesis, the structure of 1H-imidazolo [4,5-d] pyrazine has often attracted the attention of researchers. Due to its unique structure, it can be used as a key intermediate for the preparation of bioactive compounds, such as some pharmaceutical molecules, pesticide ingredients, etc. Chemists have carefully constructed this structure through various organic synthesis methods, and then modified and derived it to obtain target products that meet different needs. In conclusion, the chemical structure of 1H-imidazolo [4,5-d] pyrazine is of great significance in organic chemistry research and related application fields.
    What are the main physical properties of 1H-Imidazo [4,5-d] pyrazine?
    1H-imidazolo [4,5-d] pyrazine has many important physical properties. Its form is usually solid, and it is mostly stable at room temperature.
    The melting point of the compound containing this structure varies depending on the substituent. Generally speaking, the melting point of the compound containing this structure is quite high, or due to the strong interaction between molecules, such as hydrogen bonds, van der Waals forces, etc., high energy is required to break this effect and turn the solid state into a liquid state.
    In terms of solubility, 1H-imidazolo [4,5-d] pyrazine has limited solubility in water. Because its molecular structure is rich in aromatic rings, it has certain hydrophobicity. However, some organic solvents, such as dichloromethane, N, N-dimethylformamide, can have good solubility. This is because the organic solvent can form a suitable interaction with the compound molecules to promote its dispersion.
    In addition, its spectral properties are also key. In infrared spectroscopy, specific chemical bond vibrations can generate characteristic absorption peaks, such as nitrogen-hydrogen bonds, carbon-nitrogen bonds and other vibrational peaks, which can provide important clues for structural identification. In nuclear magnetic resonance spectroscopy, hydrogen and carbon atoms in different chemical environments exhibit unique chemical shifts, which help to analyze the spatial structure and connection of molecules.
    These physical properties are of great significance in chemical synthesis, drug development and other fields. By understanding their physical properties, researchers can better design experiments and select appropriate reaction conditions to achieve efficient synthesis and purification of target compounds, laying the foundation for the development of related fields.
    Where is 1H-Imidazo [4,5-d] pyrazine used?
    1H-imidazolo [4,5-d] pyrazine has wonderful uses in medicine, materials, chemical industry and other fields.
    In the field of medicine, this compound exhibits significant biological activity due to its unique molecular structure. Many studies have shown that it may have anti-cancer potential, and can inhibit tumor growth by interfering with the proliferation, differentiation and apoptosis pathways of cancer cells. And it also has potential therapeutic value for neurological diseases, or can regulate the release and transmission of neurotransmitters, and improve diseases such as Alzheimer's disease and Parkinson's disease. And because of its antibacterial and antiviral activities, it can develop new anti-infective drugs to deal with the increasingly serious problems of drug-resistant bacteria and virus infections.
    In the field of materials, 1H-imidazolo [4,5-d] pyrazine can be used as a building block to prepare functional materials. Its structure contains conjugated systems and electron-rich heterocycles, which can endow materials with excellent photoelectric properties. The luminescent materials prepared from this raw material are widely used in organic Light Emitting Diodes (OLEDs), which can improve the luminous efficiency and stability of devices. In terms of sensor materials, it can interact specifically with specific analytes, causing changes in the optical and electrical properties of the materials, thereby realizing highly sensitive detection of substances.
    In the chemical industry, 1H-imidazolo [4,5-d] pyrazine can be used as a high-efficiency catalyst or ligand. In organic synthesis reactions, it can effectively catalyze various chemical reactions, such as the formation of carbon-carbon bonds and carbon-heteroatomic bonds, improve reaction efficiency and selectivity, reduce production costs, and conform to the concept of green chemistry. Due to its structural stability and unique electronic properties, it can participate in many complex chemical processes, contributing to chemical product innovation and process optimization.
    What are the synthesis methods of 1H-Imidazo [4,5-d] pyrazine
    The synthesis method of 1H-imidazolo [4,5-d] pyrazine has been around for a long time, but its method has evolved with the changes of the times. In the past, people mostly followed the traditional chemical synthesis path.
    First, the nitrogen-containing heterocyclic compound is used as the starting material and the product can be obtained after a multi-step reaction. At the beginning, it is necessary to precisely select the appropriate raw materials, and through the condensation reaction, the molecular structure can be initially constructed. This condensation reaction may be carried out under the action of a specific temperature and catalyst. The catalyst can promote the reaction rate to increase, making the reaction more likely to occur. And the control of temperature is extremely critical, too high or too low will affect the reaction effect.
    Second, the oxidation cyclization step is also indispensable. After condensation, the intermediate needs to be cyclized within the molecule under specific oxidation conditions to form the unique structure of imidazolo [4,5-d] pyrazine. In this process, the choice and amount of oxidizing agent have a great impact on the purity and yield of the product. If the amount of oxidizing agent is improper, it may cause excessive oxidation and form impurities, which will affect the quality of the product.
    Furthermore, with the development of science and technology, modern synthetic methods have also emerged. For example, with the help of microwave radiation technology, the reaction time can be significantly shortened and the reaction efficiency can be improved. Microwave radiation can quickly heat the reaction system and intensify the molecular movement, thereby accelerating the reaction process. And this technology can precisely control the reaction conditions and reduce the occurrence of side reactions.
    There are also metal catalytic synthesis methods. The selection of specific metal catalysts can selectively promote the reaction and improve the selectivity and yield of the product. Metal catalysts, with their unique electronic structure, can interact with reactant molecules and guide the reaction to occur in a specific path, which is the essence of metal catalysis. All synthesis methods have advantages and disadvantages, and need to be carefully selected according to actual needs and conditions.
    What is the market outlook for 1H-Imidazo [4,5-d] pyrazine?
    1H-imidazolo [4,5-d] pyrazine, although this substance is rarely heard of, it is gradually emerging in the field of pharmaceutical and chemical industry.
    Looking at the current market situation, the prospect of this compound is quite promising. First, in the process of innovative drug research and development, its unique chemical structure is like unlocking the key to new pharmacological activities. Many scientific research teams have dedicated themselves to studying, hoping to use its framework to create new drugs with excellent curative effect and precise targets to overcome stubborn diseases such as tumors and neurodegenerative diseases. Therefore, there is a growing demand at the forefront of pharmaceutical research and development.
    Furthermore, in the field of materials science, 1H-imidazolo [4,5-d] pyrazine has also emerged. Its special physical and chemical properties make it the cornerstone of building high-performance functional materials, such as used in luminescent materials, sensors and other fields, injecting new flows into the upgrading of related industries.
    However, the rise of the market is also accompanied by various challenges. The complexity of the synthesis process and the high cost are like roadblocks, restricting its large-scale production and wide application. However, researchers are working tirelessly to simplify the process, reduce costs, and smooth its market circulation.
    From this perspective, although 1H-imidazolo [4,5-d] pyrazine is in the early stages of development, with its potential value in the field of medicine and materials, over time and with the industry's hard work, it will be able to occupy a place in the market and bloom.